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- Fall Muster at Fort D – Labor Day Weekend | Sept. 1 – 9:00am-3:00pm
- Free Attendance, Fort D Historical Site
- Nature Rx: Yoga at the Nature Center | Sept. 4 – 6:00-7:00pm
- Free Upon Registration, Cape Girardeau Nature Center
- Jackson Food Truck Rally | Sept 4 & 25 – 3:30-7:30pm
- Free Admission, 252 E. Jackson Blvd – Jackson, MO
- Brito & Yount | Sep. 5 – 7:30-9:30pm
- Free Attendance, Shuck Recital Hall
- Fall Tunes at Twilight | Sept. 6 – 6:30-7:00pm
- Free Attendance, Ivers Square Gazebo
- An Evening with Sara Evans | Sept. 6 – 7:00-10:00pm
- $55-95/tix, Century Casino Event Center
- Rockin’ in the Rock Garden Concert Series | Sept. 6 – 7:30-10:00pm
- Free Attendance, Nick Leist Memorial Band Shell
- 2024 SEMO District Fair | Sept. 7-14 – 11:00am-9:30pm
- Free Admission, 410 Kiwanis Drive – Cape Girardeau, MO
- Electric Vehicle Car Show | Sept. 14 – 3:00-9:00pm
- Free Attendance, Century Casino
- 46th Annual Manifolds on Main Street Car Show | Sept. 15 – 9:00am-4:00pm
- Free Attendance, Main Street, Cape Girardeau, MO
- Trios by Twilight | Sept. 19 – 7:30-9:30pm
- Free Admission, Shuck Recital Hall
- ND4SPD Exotic Car Show | Sept. 21 – 11:00am-2:00pm
- Free Attendance, Century Casino
- HCAM Presents: Noises Off (MATURE CONTENT) | Sept. 26-29 – Performance Times Vary
- Ticket Prices Vary, Donald C. Bedell Performance Hall
- Cape Girardeau Riverfront Flea Market | Sept. 28 – 8:00am-4:00pm
- Free Admission, Cape Girardeau Riverfront
- Symphony Sampler | Sept. 29 – 3:00-5:00pm
Free Admission, Shuck Recital Hall